Deoxypodophyllotoxin (DPT) is a potential anti-tumor candidate prior to its clinical phase. The aim of the study was to develop a physiologically-based pharmacokinetic (PBPK) model consisting of 13 tissue compartments to predict DPT disposition in mouse. rat. monkey and dog based on in vitro and in silico inputs. https://www.lightemupsequences.com/quick-find-Our-Seasons-The-World-in-Winter-Spring-Summer-and-Autumn-best-save/