There is an interest in identifying Anaphase Promoting-Complex/Cyclosome (APC/C) inhibitors that lead to sensitivity to microtubule poisons as a strategy for targeting cancer cells. Using budding yeast Saccharomyces cerevisiae. peptides derived from the Mitotic Arrest Deficient 2 (Mad2)-binding motif of Cell Division Cycle 20 (Cdc20) were observed to inhibit both Cdc20- and CDC20 Homo... https://www.roneverhart.com/HP-Pavilion-15-eg2373cl-15-6-FHD-Touch-Laptop-Intel-Core-i7-1255U-3-50-GHz-GeForce-MX550-16GB-DDR4-512GB-SSD-Windows--p8309/
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